Name: Dr. Han Lin
Institution: Northwest A&F University
Address: 28# Xinong Road, Yangling, Shaanxi, China
Phone: 0086-029-58102522
Email: hanlin2019@nwafu.edu.cn
Profile
Dr. Lin Han is an associate professor with extensive experience in molecular nutrition and health food research. He is currently working at College of Food Science and Engineering, Northwest A&F University, Shaanxi, China. His main research direction and interests are investigating molecular mechanisms of the active substances, including polyphenols and flavonoids in the cereal, to prevent and improve chronic diseases, especially obesity-related diseases, such as non-alcoholic fatty liver disease (NAFLD), diabetes and cardiovascular disease (CVD). The extensive project utilizes multi-omics techniques, including metagenomics, transcriptomics, proteomics, and metabolomics to analyze samples from animal and cell culture models that treated with or without active substances. Dr. Han is the member of Chinese Society of Nutrition, the Guest Editor of Nutrients (IF 6.706, 2022), the editorial board member of Food Nutritional Chemistry. He has published more than 30 peer-reviewed articles (first or corresponding author) with the h-index of 17 and 742 total citations (2023.8).
Experience history
Associate professor 2019– Now
College of Food Science and Engineering, Northwest A&F University, Shaanxi, China
Lecturer 2010– 2015
Chongqing Three Gorges University
Education
Ph. D of Food Science 2015-2019
Northwest A&F University, Shaanxi, China
Masters of Food Science 2007-2010 Hainan University, Hainan, China
Bachelor of Food Science and Engineering 2003-2007
Hainan University, Hainan, China
Part of the recent publications
Lin Han*, Huiqing Wang*, Junwei Cao, et al. Inhibition mechanism of α-glucosidase inhibitors screened from Tartary buckwheat and synergistic effect with acarbose. Food Chemistry, 2023, 420, 136102 (* co-first author). (IF2023=9.231, JCR Q1)
Caian He , Xiaojiao Liu, Haiyan Zhang, ,…, Lin Han*, Min Wang*. Enhancement of the release of phenolic compounds from white and black Qingke bran by autoclaving and fermentation treatments. Food Bioscience, 2023, 53, 102696 (IF2023=5.200, JCR Q1).
Yao Xiao, Kailin Li, Ji Bian,…, Lin Han#, Lan Gong#, Min Wang#.Urolithin A attenuates diabetes-associated cognitive impairment by amelioratingintestinal barrier dysfunction via N-glycan biosynthesis pathway. Molecular Nutrition & Food Research, 2022, 2100863(# corresponding author). (IF2022=6.575, JCR Q1)
Qiong Yang, Yao Zhang, Luqi Li,…, Lin Han#, Min Wang#. D-chiro-Inositol facilitates adiponection biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition. Food & Function, 2022, 13, 7192-7203 (# corresponding author). (IF2022=6.317, JCR Q1)
Lin Han, Yao Zhang, Jia Li, et al. Phloretin attenuation of hepatic steatosis via an improvement of mitochondrial dysfunction by activating AMPK-dependent signaling pathways in C57BL/6J mice and HepG2 cells. Food & Function, 2021, 12, 12421-12433. (IF2021=6.317, JCR Q1)
Lin Han, Jie Li, Jia Li, et al. Activation of AMPK/Sirt3 pathway by phloretin reduces mitochondrial ROS in vascular endothelium by increasing the activity of MnSOD via deacetylation. Food & Function. 2020, 11, 3073-3083. (IF2020=5.396, JCR Q1)
Lin Han, Qing Yang, Jia Li, et al. Protocatechuic acid ameliorates endothelial oxidative stress through regulating acetylation level via CD36/AMPK pathway. Journal of Agricultural and Food Chemistry. 2019, 67, 7060-7072. (IF2019=4.192, JCR Q1)
Lin Han, Qing Yang, Wenfang Ma, et al. Protocatechuic acid ameliorated palmitic acid induced oxidative damage in endothelial cells through activating endogenous antioxidant enzymes via an adenosine-monophosphate-activated-protein-kinase-dependent pathway. Journal of Agricultural and Food Chemistry. 2018, 40, 10400-10409. (IF2018=3.571, JCR Q1)
Lin Han, Lingling Zhang, Wenfang Ma, et al. Proanthocyanidin B2 attenuates postprandial blood glucose and its inhibitory effect on alpha-glucosidase: analysis by kinetics, fluorescence spectroscopy, atomic force microscopy and molecular docking. Food & Function. 2018, 9, 4673-4682. (IF2018=3.241, JCR Q1)
Lin Han, Chun Fang, Ruixue Zhu, et al. Inhibitory effect of phloretin on α-glucosidase: kinetics, interaction mechanism and molecular docking. International Journal of Biological Macromolecules. 2017, 95, 520-527. (IF2017=3.909, JCR Q1)
Lingling Zhang*, Lin Han*, Shiyi Yang, et al. The mechanism of interactions between flavan-3-ols against α-glucosidase and their in vivo antihyperglycemic effects. Bioorganic Chemistry, 2019, 85, 364-372 (* co-first author). (IF2019=4.831, JCR Q2)
